Experimental loss of menisci, cartilage and subchondral bone gradually increases anteroposterior knee laxity
نویسندگان
چکیده
منابع مشابه
Immature articular cartilage and subchondral bone covered by menisci are potentially susceptive to mechanical load
BACKGROUND The differences of mechanical and histological properties between cartilage covered by menisci and uncovered by menisci may contribute to the osteoarthritis after meniscectomy and these differences are not fully understood. The purpose of this study is to investigate potential differences in the mechanical and histological properties, and in particular the collagen architecture, of t...
متن کاملDistribution of subchondral bone density and cartilage
Subchondral bone density (by means of CT osteoabsorptiometry), and cartilage thickness (directly measured on photocopies of frozen sections), were examined in 30 human patellae, with an age range from 47 to 90 y. A surface demonstration of the distribution was prepared, and representative pictures produced by summation with a computer. Subchondral bone-density maxima were found in the proximal ...
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Unlike knee plain radiography which can only detect joint space narrowing and osteophytes, magnetic resonance imaging can directly visualize and analyse the whole knee structure, including bone size, cartilage defects and loss of cartilage volume. Tibial subchondral bone area expansion may be primary and is associated with risk factors such as age, body mass index (BMI), genetics and/or limb ma...
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Subchondral bone reabsorption and remodeling are responsible for the initiation and progression of osteoarthritis (OA). Zoledronic acid (ZOL), a third-generation bisphosphonate (BIS), is an inhibitor of bone reabsorption. However, the intervention effect of ZOL on OA has not been fully characterized and remains to be directly demonstrated in animal experiments. The present study examined the mi...
متن کاملSubchondral Bone Sclerosis Increases In Both Trabecular Bone And Subchondral Plate In Human Knee Osteoarthritis : Relationship With Histology
Introduction: Osteoarthritis (OA) is a disease of a whole joint. Yet most of the diagnostic methods are focused mainly on cartilage degeneration and erosion. However, there is increasing evidence that the subchondral bone significantly contributes to the pathogenesis of OA. It has even been suggested that first tissue-level changes in OA occur in the subchondral bone before any signs of degener...
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ژورنال
عنوان ژورنال: Knee Surgery, Sports Traumatology, Arthroscopy
سال: 2011
ISSN: 0942-2056,1433-7347
DOI: 10.1007/s00167-011-1799-z